SCHEMBL15426481

SCHEMBL15426481

Cc1ccc(NC(=O)C(C)(C)C)c(Cl)n1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ CETP P11597 1/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ KDM4E B2RXH2 2/20 0.41
▸ MITF O75030 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ KLF5 Q13887 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ HTT P42858 2/20 0.41
▸ RAB9A P51151 1/20 0.39
▸ ADORA1 P30542 1/20 0.39
▸ MAPT P10636 2/20 0.39
▸ TP53 P04637 1/20 0.39
▸ EGFR P00533 3/20 0.38
▸ LMNA P02545 2/20 0.37
▸ TOP2A P11388 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31146057 0.80 L3MBTL1 (0.44) L3MBTL1CETPKDM4EALDH1A1ADORA1
SCHEMBL23628497 0.80 L3MBTL1 (0.44) L3MBTL1CETPKDM4EALDH1A1HTT
SCHEMBL9952130 0.80 CYP1A2 (0.43) L3MBTL1CETPMEN1KMT2AKDM4E
SCHEMBL14782288 0.80 L3MBTL1 (0.41) L3MBTL1CETPMEN1KMT2AKDM4E
SCHEMBL31145979 0.79 L3MBTL1 (0.43) L3MBTL1CETPKDM4EADORA1MAPT
SCHEMBL23628469 0.78 KDM4E (0.46) L3MBTL1CETPKDM4EALDH1A1HPGD
SCHEMBL20708733 0.77 PDK1 (0.45) L3MBTL1KDM4EMITFALDH1A1HPGD
SCHEMBL18976912 0.74 POLB (0.38) SMN1; SMN2RAB9AMAPTEGFR
SCHEMBL9792253 0.74 NPC1 (0.56) MEN1KMT2AALDH1A1HPGDSMN1; SMN2
SCHEMBL25219070 0.73 L3MBTL1 (0.41) L3MBTL1CETPMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278983-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-08 — — US disclosed
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-11 — — US disclosed
US-8853238-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-07 — — US disclosed
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF NR4A1, NR2C2, NR0B1 L3MBTL1 31/4885CETP 4171/4885MEN1 767/4885
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL NR4A1, NR2C2, NR0B1 L3MBTL1 33/4885CETP 4173/4885MEN1 795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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