Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043018 | 0.79 | KDM4E (0.62) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL21827130 | 0.79 | KDM4E (0.45) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL18587265 | 0.76 | CYP2D6 (0.51) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL18587062 | 0.76 | KDM4E (0.44) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL29738716 | 0.76 | CYP2D6 (0.51) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL106226 | 0.74 | KDM4E (0.51) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL18544196 | 0.73 | KDM4E (0.42) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL5377178 | 0.71 | KDM4E (0.47) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL18586975 | 0.69 | KDM4E (0.47) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL18609664 | 0.69 | ALDH1A1 (0.51) | KDM4EMEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068296-A | Crosslinked copolymers for molding materials | HERCULES INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| US-5006616-A | Metathesis polymerized copolymer | HERCULES INCORPORATED (US) | 1991-04-09 | — | — | US | disclosed |
| US-4994535-A | Molding material | HERCULES INCORPORATED (US) | 1991-02-19 | — | — | US | disclosed |
| US-4923943-A | DICYCLOPENTADIENE, NORBORNENYL ESTERS OF NORBORNENYL ACIDS | HERCULES INCORPORATED (US) | 1990-05-08 | — | — | US | disclosed |
| US-4918138-A | Process for producing a colored molded article of metathesis polymerized polymer | HERCULES INCORPORATED (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0349855-A2 | Molded article of metathesis polymerized polymer containing fillers and process for its preparation | HERCULES INCORPORATED (US) | 1990-01-10 | — | — | EP | disclosed |
| EP-0329063-A2 | Process for producing a colored molded article of metathesis polymerized polymer | HERCULES INCORPORATED (US) | 1989-08-23 | — | — | EP | disclosed |
| EP-0305933-A2 | Process for producing a molded article of metathesis polymerized polymer | HERCULES INCORPORATED (US) | 1989-03-08 | — | — | EP | disclosed |
| EP-0287762-A2 | Methathesis polymerized copolymer | HERCULES INCORPORATED (US) | 1988-10-26 | — | — | EP | disclosed |
| EP-0286839-A1 | Metathesis polymerized copolymer | HERCULES INCORPORATED (US) | 1988-10-19 | — | — | EP | disclosed |
| EP-0280247-A2 | Metathesis polymerization | HERCULES INCORPORATED (US) | 1988-08-31 | — | — | EP | disclosed |