Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP3CA | Q08209 | 6/20 | 0.87 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.86 |
| ▸ | PPIA | P62937 | 4/20 | 0.86 |
| ▸ | MEN1 | O00255 | 1/20 | 0.86 |
| ▸ | NPC1 | O15118 | 1/20 | 0.86 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.86 |
| ▸ | GMNN | O75496 | 1/20 | 0.86 |
| ▸ | USP2 | O75604 | 1/20 | 0.86 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.86 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.86 |
| ▸ | LMNA | P02545 | 1/20 | 0.86 |
| ▸ | POLB | P06746 | 1/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.86 |
| ▸ | MAPT | P10636 | 1/20 | 0.86 |
| ▸ | RARB | P10826 | 1/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.86 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.86 |
| ▸ | TACR2 | P21452 | 1/20 | 0.86 |
| ▸ | PPIB | P23284 | 1/20 | 0.86 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9929569 | 0.95 | PPP3CA (0.87) | PPP3CAABCB1PPIAMEN1NPC1 | |
| SCHEMBL9929568 | 0.95 | PPP3CA (0.87) | PPP3CAABCB1PPIAMEN1NPC1 | |
| SCHEMBL11957346 | 0.95 | PPP3CA (0.87) | PPP3CAABCB1PPIAMEN1NPC1 | |
| SCHEMBL11957320 | 0.95 | PPP3CA (0.87) | PPP3CAABCB1PPIAMEN1NPC1 | |
| SCHEMBL11978794 | 0.94 | PPP3CA (0.86) | PPP3CAABCB1PPIAMEN1NPC1 | |
| Cyclosporine SCHEMBL4454862 | 0.94 | ABCB1 (0.96) | PPP3CAABCB1PPIAMEN1NPC1 | |
| Cyclosporine SCHEMBL2973381 | 0.93 | ABCB1 (0.95) | PPP3CAABCB1PPIAMEN1NPC1 | |
| Cyclosporine SCHEMBL2973383 | 0.93 | ABCB1 (0.95) | PPP3CAABCB1PPIAMEN1NPC1 | |
| SCHEMBL11979272 | 0.93 | PPP3CA (0.84) | PPP3CAABCB1PPIAMEN1NPC1 | |
| Cyclosporine SCHEMBL24239446 | 0.93 | ABCB1 (1.00) | PPP3CAABCB1PPIAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196749-A1 | Cyclosporin Derivatives | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-08-02 | — | — | US | disclosed |
| US-20120058932-A1 | ACTIVE INGREDIENT-PEPTIDE CONSTRUCT FOR EXTRACELLULAR CONCENTRATION | MAX PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196749-A1 | Cyclosporin Derivatives | TSLP, FKBP14, CHP1 | PPP3CA 512/4885ABCB1 35/4885PPIA 59/4885 |
| US-20120058932-A1 | ACTIVE INGREDIENT-PEPTIDE CONSTRUCT FOR EXTRACELLULAR CONCENTRATION | VIP, FIBP, MMP7 | PPP3CA 4171/4885ABCB1 1204/4885PPIA 1604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.