Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10417398 | 0.99 | GPR35 (0.44) | GPR35GAAPTGDR2ALDH1A1TSHR | |
| SCHEMBL11665258 | 0.86 | KMT2A (0.48) | GPR35GAAALDH1A1TSHRTP53 | |
| SCHEMBL13172174 | 0.84 | S1PR4 (0.49) | GAAPTGDR2ALDH1A1CYP1A2KDM4E | |
| Hydrochloric Acid SCHEMBL11360528 | 0.83 | TDP1 (0.52) | GAAPTGDR2ALDH1A1TSHRCYP1A2 | |
| SCHEMBL30764067 | 0.79 | TSHR (0.59) | GPR35GAAPTGDR2ALDH1A1TSHR | |
| SCHEMBL9794582 | 0.79 | TSHR (0.59) | GPR35GAAPTGDR2ALDH1A1TSHR | |
| SCHEMBL20589129 | 0.79 | GAA (0.41) | GAAPTGDR2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11358987 | 0.78 | SMN1; SMN2 (0.51) | GAAALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL11149431 | 0.78 | KMT2A (0.51) | GPR35GAAALDH1A1TSHRTP53 | |
| SCHEMBL1496537 | 0.77 | GAA (0.68) | GAAALDH1A1MAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985042-A | New substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process | L'OREAL (FR) | 1991-01-15 | — | — | US | disclosed |
| US-4954131-A | Substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process | L'OREAL (FR) | 1990-09-04 | — | — | US | disclosed |
| US-4863480-A | OXIDATION COLOR DYES | THE FRENCH JOINT STOCK COMPANY "L'OREAL" (FR) | 1989-09-05 | — | — | US | disclosed |