Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655839 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL30950239 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL9794635 | 0.73 | CTSB (0.46) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL9794622 | 0.69 | ALDH1A1 (0.39) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL5794239 | 0.68 | KDM4E (0.60) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL8676980 | 0.66 | ALDH1A1 (0.44) | ALDH1A1TTRHIF1APOLB | |
| Water SCHEMBL242080 | 0.66 | TTR (0.72) | MEN1KMT2AALDH1A1TTRCOMT | |
| Water SCHEMBL31290656 | 0.66 | TTR (0.72) | MEN1KMT2AALDH1A1TTRCOMT | |
| Water SCHEMBL29809771 | 0.66 | TTR (0.72) | MEN1KMT2AALDH1A1TTRCOMT | |
| Water SCHEMBL29893556 | 0.66 | TTR (0.72) | MEN1KMT2AALDH1A1TTRCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252350-B1 | 3-CYANOQUINOLINE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-01-02 | — | — | EP | disclosed |
| EP-0252350-A1 | 3-Cyanoquinoline derivatives | BASF Aktiengesellschaft (DE) | 1988-01-13 | — | — | EP | disclosed |