Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30950239 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL31636670 | 0.84 | KDM4E (0.44) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL25805402 | 0.78 | MEN1 (0.37) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9794630 | 0.76 | MEN1 (0.42) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9794635 | 0.75 | CTSB (0.46) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL2712037 | 0.75 | MAPT (0.43) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5794239 | 0.73 | KDM4E (0.60) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL558684 | 0.72 | MAPT (0.40) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL30950214 | 0.71 | ENPP1 (0.48) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL28676590 | 0.71 | ENPP1 (0.48) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113637005-B | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-113637005-A | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2021-11-12 | — | — | CN | disclosed |