Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.58 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9794690 | 0.95 | FDPS (0.65) | FDPSLTA4H | |
| SCHEMBL9806694 | 0.78 | FDPS (0.90) | FDPS | |
| SCHEMBL6890158 | 0.76 | FDPS (0.63) | FDPS | |
| SCHEMBL8703776 | 0.73 | FDPS (1.00) | FDPS | |
| SCHEMBL18398793 | 0.73 | CHRNA3 (0.46) | CHRNA3CHRNB4CHRNB2LTA4H | |
| SCHEMBL8663342 | 0.73 | FDPS (0.47) | FDPSCHRNA3CHRNB4CHRNB2CHRNA5 | |
| SCHEMBL14780049 | 0.73 | LTA4H (0.43) | CHRNA3CHRNB4CHRNB2LTA4H | |
| SCHEMBL14780047 | 0.73 | LTA4H (0.43) | CHRNA3CHRNB4CHRNB2LTA4H | |
| SCHEMBL18501111 | 0.73 | FDPS (0.47) | FDPSCHRNA3CHRNB4CHRNB2CHRNA5 | |
| SCHEMBL3429831 | 0.73 | FDPS (0.47) | FDPSCHRNA3CHRNB4CHRNB2CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002937-A | Diphosphonic acid alkyloxyalkylamines for bone disorders | BOEHRINGER MANNHEIM GMBH (DE) | 1991-03-26 | — | — | US | disclosed |
| EP-0350002-A1 | Diphosphonic-acid derivatives, process for their preparation and medicines containing those compounds | Roche Diagnostics GmbH (DE) | 1990-01-10 | — | — | EP | disclosed |