Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 18/20 | 0.72 |
| ▸ | ATIC | P31939 | 1/20 | 0.55 |
| ▸ | FOLR2 | P14207 | 1/20 | 0.49 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.49 |
| ▸ | SLC46A1 | Q96NT5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9794858 | 1.00 | GART (0.72) | GARTATICFOLR2FOLR1SLC46A1 | |
| SCHEMBL9794846 | 0.88 | GART (0.73) | GARTATICFOLR2FOLR1SLC46A1 | |
| SCHEMBL9794843 | 0.88 | GART (0.73) | GARTATICFOLR2FOLR1SLC46A1 | |
| SCHEMBL7615333 | 0.88 | GART (0.57) | GARTFOLR2FOLR1SLC46A1 | |
| SCHEMBL7607120 | 0.86 | GART (0.71) | GARTATICFOLR1 | |
| SCHEMBL9794844 | 0.84 | GART (1.00) | GARTATICFOLR2FOLR1SLC46A1 | |
| SCHEMBL7609761 | 0.83 | GART (0.70) | GARTATICFOLR2FOLR1SLC46A1 | |
| SCHEMBL7609759 | 0.83 | GART (0.70) | GARTATICFOLR2FOLR1SLC46A1 | |
| SCHEMBL9794872 | 0.80 | GART (0.58) | GARTATIC | |
| SCHEMBL7609490 | 0.80 | GART (0.55) | GARTFOLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409382-A1 | Glutamic acid derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-01-23 | — | — | EP | disclosed |
| US-4921836-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1990-05-01 | — | — | US | disclosed |