Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795120 | 1.00 | GNAI3 (0.46) | GNAI3GNAO1GNAI1NAAACHRNB2 | |
| SCHEMBL9795532 | 1.00 | GNAI3 (0.46) | GNAI3GNAO1GNAI1NAAACHRNB2 | |
| SCHEMBL3794825 | 0.92 | GNAI3 (0.50) | GNAI3GNAO1GNAI1NAAACHRNB2 | |
| SCHEMBL9795156 | 0.89 | KMT2A (0.42) | GNAI3GNAO1GNAI1NAAAKMT2A | |
| SCHEMBL9795353 | 0.89 | KMT2A (0.42) | GNAI3GNAO1GNAI1NAAAKMT2A | |
| SCHEMBL9795164 | 0.89 | KMT2A (0.42) | GNAI3GNAO1GNAI1NAAAKMT2A | |
| SCHEMBL8352626 | 0.85 | PLG (0.47) | GNAI3GNAO1GNAI1NAAACHRNB2 | |
| SCHEMBL13432005 | 0.85 | NAAA (0.56) | GNAI3GNAO1GNAI1NAAACHRNB2 | |
| SCHEMBL16357639 | 0.85 | NAAA (0.61) | GNAI3GNAO1GNAI1NAAACHRNB2 | |
| SCHEMBL13300769 | 0.83 | NAAA (0.64) | GNAI3GNAO1GNAI1NAAACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |