Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795353 | 1.00 | KMT2A (0.42) | KMT2AGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL9795164 | 1.00 | KMT2A (0.42) | KMT2AGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL4679423 | 0.92 | — | — | |
| SCHEMBL9795532 | 0.89 | GNAI3 (0.46) | KMT2AGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL9795113 | 0.89 | GNAI3 (0.46) | KMT2AGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL9795120 | 0.89 | GNAI3 (0.46) | KMT2AGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL4678443 | 0.83 | NAAA (0.55) | KMT2AGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL4679015 | 0.83 | NAAA (0.50) | KMT2AGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL15305136 | 0.82 | GNAI3 (0.43) | KMT2AGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL23419143 | 0.82 | NAAA (0.58) | KMT2ANAAAEPHX1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |