Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953975 | 0.94 | CNR1 (0.51) | CNR1BLMKMT2AALDH1A1MEN1 | |
| Oxalic Acid SCHEMBL9795286 | 0.90 | CNR1 (0.44) | CNR1BLMKMT2AGABRR3GABRP | |
| SCHEMBL19860859 | 0.90 | CNR1 (0.49) | CNR1BLMKMT2AALDH1A1MEN1 | |
| SCHEMBL10965153 | 0.88 | SLC6A5 (0.51) | CNR1BLMKMT2AALDH1A1MEN1 | |
| Oxalic Acid SCHEMBL9795417 | 0.88 | CNR2 (0.41) | CNR1BLMKMT2ALMNATSHR | |
| Oxalic Acid SCHEMBL7536073 | 0.86 | SLC6A5 (0.44) | CNR1TSHRCA1CA2SLC6A5 | |
| Oxalic Acid SCHEMBL8024643 | 0.86 | SLC6A5 (0.44) | CNR1TSHRCA1CA2SLC6A5 | |
| Phosphoric Acid SCHEMBL10889003 | 0.86 | CNR1 (0.46) | CNR1BLMKMT2AALDH1A1MEN1 | |
| SCHEMBL8830428 | 0.86 | SLC6A5 (0.54) | CNR1BLMKMT2ALMNATHRB | |
| SCHEMBL27101191 | 0.86 | SLC6A5 (0.54) | CNR1BLMKMT2ALMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |