Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8024643 | 1.00 | SLC6A5 (0.44) | SLC6A5NAAACNR1TSHRDNM1 | |
| SCHEMBL10594732 | 0.94 | SLC6A5 (0.47) | SLC6A5NAAACNR1TSHRDNM1 | |
| Oxalic Acid SCHEMBL9795286 | 0.92 | CNR1 (0.44) | SLC6A5NAAACNR1TSHRDNM1 | |
| SCHEMBL17230156 | 0.88 | SLC6A5 (0.50) | SLC6A5NAAACNR1TSHRDNM1 | |
| SCHEMBL30406271 | 0.86 | SLC6A5 (0.53) | SLC6A5NAAACNR1DNM1PAOX | |
| SCHEMBL10795093 | 0.86 | SLC6A5 (0.53) | SLC6A5NAAACNR1DNM1PAOX | |
| Oxalic Acid SCHEMBL9795138 | 0.86 | CNR1 (0.47) | SLC6A5CNR1TSHRCA1CA2 | |
| SCHEMBL7844220 | 0.85 | NAAA (0.52) | SLC6A5NAAACNR1TSHRDNM1 | |
| Oxalic Acid SCHEMBL9795198 | 0.85 | FNTA (0.44) | SLC6A5NAAACNR1DNM1 | |
| SCHEMBL27406932 | 0.84 | NAAA (0.59) | SLC6A5NAAATSHRPAOXKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919555-B1 | Process for the preparation of bicyclic amidines, diazacycloalkenes and a process for their preparation | BASF AG (DE) | 2002-05-08 | — | — | EP | disclosed |
| US-6166207-A | Preparation of bicyclic amidines and diazacycloalkenes | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |
| EP-0919555-A1 | Process for the preparation of bicyclic amidines, diazacycloalkenes and a process for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-02 | — | — | EP | disclosed |