Phosphoric Acid

Phosphoric Acid

SCHEMBL10889003

NCCCC(=O)NCCO.O=P(O)(O)O

nearest known ligand 0.46

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.46
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 2/20 0.41
BLM P54132 2/20 0.41
KMT2A Q03164 2/20 0.41
TRPV1 Q8NER1 2/20 0.41
SELP P16109 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
FAAH O00519 1/20 0.41
KCNK3 O14649 1/20 0.41
CNR2 P34972 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
HPGD P15428 2/20 0.41
MAPT P10636 1/20 0.41
ALOX12 P18054 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SLC6A5 Q9Y345 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8953975 0.92 CNR1 (0.51) CNR1ALDH1A1MEN1BLMKMT2A
Phosphoric Acid SCHEMBL11427044 0.91 CNR1 (0.43) CNR1CNR2CA1CA2SLC6A5
SCHEMBL19860859 0.88 CNR1 (0.49) CNR1ALDH1A1MEN1BLMKMT2A
Phosphoric Acid SCHEMBL6916276 0.88 CNR1 (0.40) CNR1ALDH1A1MEN1BLMKMT2A
Oxalic Acid SCHEMBL9795138 0.86 CNR1 (0.47) CNR1ALDH1A1MEN1BLMKMT2A
SCHEMBL10965153 0.86 SLC6A5 (0.51) CNR1ALDH1A1MEN1BLMKMT2A
SCHEMBL8830428 0.84 SLC6A5 (0.54) CNR1ALDH1A1MEN1BLMKMT2A
SCHEMBL27101191 0.84 SLC6A5 (0.54) CNR1ALDH1A1MEN1BLMKMT2A
Phosphoric Acid SCHEMBL11422019 0.81 NAAA (0.43) CNR1CA1CA2SLC6A5
SCHEMBL24761185 0.79 SLC6A5 (0.51) ALDH1A1MEN1BLMKMT2AFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4102948-A DECREASE BLOOD SUGAR CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1978-07-25 US claimed
US-4563479-A PROPHYLAXIS OR THERAPY CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYAR RT (HU) 1986-01-07 US disclosed
US-4218404-A HYPOGLYCEMIC AGENTS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1980-08-19 US disclosed
US-4102948-A DECREASE BLOOD SUGAR CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1978-07-25 US disclosed