SCHEMBL9795545

SCHEMBL9795545

CC(C)(CNC(=O)CN)COC(=O)C(=O)OCC(C)(C)CNC(=O)CN

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9795141 0.78 SMN1; SMN2 (0.31) SMN1; SMN2HSD17B10
SCHEMBL993141 0.73 CACNA1H (0.35) SMYD3
SCHEMBL6091134 0.73 KDM4E (0.52) SMYD3SMN1; SMN2HSD17B10
SCHEMBL9795503 0.73 CYP1A2 (0.36)
SCHEMBL16853203 0.72 SMYD3 (0.34) SMYD3SMN1; SMN2HSD17B10
Oxalic Acid SCHEMBL9795538 0.72 ALDH1A1 (0.37) SMYD3SMN1; SMN2HSD17B10
SCHEMBL25698379 0.72 KDM4E (0.39)
SCHEMBL9795151 0.71 KDM4E (0.33) HSD17B10
SCHEMBL19170403 0.71 PIK3CD (0.38) SMYD3
SCHEMBL23341003 0.70 CYP1A2 (0.32) SMYD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037849-A For treatment of heart and circulatory diseases BOEHRINGER MANNHEIM GMBH (DE) 1991-08-06 US disclosed