Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GSR | P00390 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795150 | 0.88 | GSR (0.40) | KMT2AGSRBCHEPOLBMEN1 | |
| SCHEMBL9795202 | 0.78 | KMT2A (0.39) | KMT2ABCHECYP1A2CYP2D6TSHR | |
| Fumaric Acid SCHEMBL9795273 | 0.75 | GSR (0.38) | GSRBCHE | |
| SCHEMBL9498011 | 0.74 | KMT2A (0.49) | KMT2AGSRBCHECYP1A2CYP2D6 | |
| SCHEMBL9795540 | 0.72 | PKM (0.38) | KMT2APOLBLMNAHSD17B10MEN1 | |
| Fumaric Acid SCHEMBL9795493 | 0.70 | GSR (0.35) | GSRBCHE | |
| SCHEMBL10567442 | 0.70 | GSR (0.56) | KMT2AGSRBCHEMEN1 | |
| SCHEMBL9795239 | 0.70 | POLB (0.48) | KMT2ABCHETSHRPOLBSIGMAR1 | |
| SCHEMBL9795334 | 0.67 | GSR (0.47) | GSRBCHETSHRTDP1 | |
| Fumaric Acid SCHEMBL9795374 | 0.66 | GSR (0.38) | GSRBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |