Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9795509 | 0.93 | POLB (0.43) | POLBTSHRLMNAKMT2ASIGMAR1 | |
| SCHEMBL9795256 | 0.86 | HSD11B1 (0.45) | POLBTSHRLMNAKMT2ATP53 | |
| SCHEMBL9795202 | 0.82 | KMT2A (0.39) | POLBTSHRLMNAKMT2ASIGMAR1 | |
| SCHEMBL9795115 | 0.81 | TSHR (0.52) | POLBTSHRLMNAKMT2ASIGMAR1 | |
| SCHEMBL9498011 | 0.81 | KMT2A (0.49) | POLBTSHRLMNAKMT2ASIGMAR1 | |
| SCHEMBL9129841 | 0.80 | LMNA (0.36) | TSHRLMNAKMT2ABCHENAAA | |
| Fumaric Acid SCHEMBL9795302 | 0.80 | HSD11B1 (0.40) | POLBTSHRLMNAKMT2ATP53 | |
| SCHEMBL9127574 | 0.79 | KMT2A (0.34) | TSHRKMT2ABCHENAAAGFER | |
| SCHEMBL9129520 | 0.78 | NAAA (0.38) | TSHRLMNAKMT2ABCHENAAA | |
| SCHEMBL9795281 | 0.77 | TSHR (0.57) | POLBTSHRLMNAKMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |