Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | ACR | P10323 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497738 | 0.94 | ANPEP (0.34) | CYP2D6CYP2C19ANPEPDNPEPALDH1A1 | |
| SCHEMBL7946066 | 0.79 | CYP2D6 (0.50) | CYP2D6CYP2C19ANPEPDNPEPALDH1A1 | |
| SCHEMBL10018013 | 0.77 | CYP2D6 (0.36) | CYP2D6CYP2C19ANPEPDNPEPALDH1A1 | |
| SCHEMBL26199046 | 0.77 | CYP2D6 (0.36) | CYP2D6CYP2C19ANPEPDNPEPALDH1A1 | |
| SCHEMBL26198366 | 0.77 | CYP2D6 (0.36) | CYP2D6CYP2C19ANPEPDNPEPALDH1A1 | |
| SCHEMBL11521154 | 0.75 | CYP2D6 (0.34) | CYP2D6CYP2C19ANPEPDNPEPALDH1A1 | |
| SCHEMBL2745754 | 0.74 | CA2 (0.35) | CYP2C19ALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL9795360 | 0.72 | CNR1 (0.36) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8225897 | 0.72 | SYK (0.32) | ANPEPDNPEP | |
| SCHEMBL8225884 | 0.72 | SYK (0.32) | ANPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |