Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497738 | 0.84 | ANPEP (0.34) | CYP2D6CYP2C19ALDH1A1ANPEPDNPEP | |
| SCHEMBL8932181 | 0.81 | CYP2D6 (0.54) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| Oxalic Acid SCHEMBL9795231 | 0.79 | CYP2D6 (0.34) | CYP2D6CYP2C19KMT2AALDH1A1MEN1 | |
| SCHEMBL8225897 | 0.78 | SYK (0.32) | ANPEPDNPEP | |
| SCHEMBL8225884 | 0.78 | SYK (0.32) | ANPEPDNPEP | |
| SCHEMBL1310832 | 0.78 | ANPEP (0.46) | MMP8KMT2AMAPTGAAMEN1 | |
| SCHEMBL9795246 | 0.78 | MAPT (0.32) | MAPT | |
| SCHEMBL25389856 | 0.77 | CYP2C19 (0.50) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL22318581 | 0.77 | CYP2D6 (0.50) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL18907825 | 0.77 | CYP2D6 (0.50) | CYP2D6CYP2C19MMP1MMP8EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100003276-A1 | Methods for treating anthrax and inhibiting lethal factor | HERMES JEFFERY D | 2010-01-07 | — | — | US | disclosed |
| US-7504425-B2 | Compounds useful in the treatment of anthrax and inhibiting lethal factor | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100003276-A1 | Methods for treating anthrax and inhibiting lethal factor | ANTXR2, SERPINB1, APAF1 | CYP2D6 4661/4885CYP2C19 4580/4885MMP1 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.