SCHEMBL9795246

SCHEMBL9795246

CC(CNC(=O)C(C)(C)N)OC(=O)C(=O)OC(C)CNC(=O)C(C)(C)N

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7946066 0.78 CYP2D6 (0.50) MAPT
SCHEMBL9497738 0.76 ANPEP (0.34)
SCHEMBL9498443 0.76 PTGS1 (0.30)
Oxalic Acid SCHEMBL9795231 0.72 CYP2D6 (0.34)
SCHEMBL8225884 0.71 SYK (0.32)
SCHEMBL8225897 0.71 SYK (0.32)
SCHEMBL2745754 0.69 CA2 (0.35) MAPT
SCHEMBL16805864 0.68 TSHR (0.38) MAPTMTNR1AMTNR1B
SCHEMBL16803337 0.68 TSHR (0.45) MAPTMTNR1AMTNR1B
SCHEMBL9795288 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037849-A For treatment of heart and circulatory diseases BOEHRINGER MANNHEIM GMBH (DE) 1991-08-06 US disclosed