Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GPX4 | P36969 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796345 | 0.99 | ALDH1A1 (0.40) | AOC3LMNATAS1R3TAS1R1PSEN1 | |
| SCHEMBL9796059 | 0.96 | PSEN1 (0.42) | AOC3LMNATAS1R3TAS1R1PSEN1 | |
| SCHEMBL9796092 | 0.88 | AOC3 (0.39) | AOC3TAS1R3TAS1R1PSEN1PSEN2 | |
| SCHEMBL16672627 | 0.84 | LMNA (0.45) | AOC3LMNAPSEN1PSEN2APH1B | |
| SCHEMBL15155229 | 0.83 | PRKCA (0.40) | ALDH1A1ALOX5PPARGPPARA | |
| SCHEMBL15155815 | 0.83 | PRKCA (0.40) | ALDH1A1ALOX5PPARGPPARA | |
| SCHEMBL9796301 | 0.83 | CNR2 (0.36) | ALDH1A1 | |
| SCHEMBL15155209 | 0.83 | PRKCA (0.40) | ALDH1A1ALOX5PPARGPPARA | |
| SCHEMBL9340624 | 0.82 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9A | |
| SCHEMBL5043409 | 0.82 | UTS2R (0.42) | LMNAALDH1A1KMT2AL3MBTL1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006534-A | Substituted ethers, thioethers and amines for use as lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |