Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796022 | 0.83 | ADAMTS4 (0.49) | NPSR1PTPN11KDM4EALDH1A1PTPN1 | |
| SCHEMBL3756242 | 0.83 | ALDH1A1 (0.55) | NPSR1PTPN11KDM4EALDH1A1TSHR | |
| SCHEMBL3714577 | 0.83 | NPSR1 (0.51) | NPSR1PTPN11KDM4EALDH1A1GFER | |
| SCHEMBL3764291 | 0.83 | NPSR1 (0.50) | NPSR1PTPN11KDM4EALDH1A1PTPN1 | |
| SCHEMBL3764440 | 0.81 | NPSR1 (0.46) | NPSR1PTPN11KDM4EALDH1A1GFER | |
| SCHEMBL3923738 | 0.80 | LMNA (0.62) | NPSR1KDM4EALDH1A1TSHRMEN1 | |
| SCHEMBL10984175 | 0.80 | NPSR1 (0.48) | NPSR1PTPN11KDM4EALDH1A1MCL1 | |
| SCHEMBL13543499 | 0.80 | CYP3A4 (0.52) | NPSR1PTPN11KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1042597 | 0.76 | LMNA (0.61) | KDM4EALDH1A1MCL1HSD17B10HPGD | |
| SCHEMBL1593800 | 0.76 | ALDH1A1 (0.72) | KDM4EALDH1A1MCL1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990523-A | Treatment of chronic inflammatory joint disease with arylsulfonamides | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-02-05 | — | — | US | disclosed |