Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796298 | 0.86 | SIGMAR1 (0.39) | SIGMAR1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL9007112 | 0.84 | KDM1A (0.33) | KDM1AMAOAMAOB | |
| SCHEMBL27543362 | 0.83 | ELANE (0.34) | OPRM1OPRD1OPRK1OPRL1KDM4E | |
| SCHEMBL31549868 | 0.81 | MMP2 (0.34) | SIGMAR1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL27262899 | 0.79 | HSD11B1 (0.35) | OPRL1HSD11B1 | |
| SCHEMBL27262487 | 0.78 | — | — | |
| SCHEMBL27262106 | 0.78 | HTR2A (0.36) | HSD11B1KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL27263234 | 0.78 | HTR2A (0.36) | HSD11B1KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL27262720 | 0.78 | HTR2A (0.36) | HSD11B1KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL27262507 | 0.78 | HTR2A (0.36) | HSD11B1KDM4EALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407569-A1 | DIPHENYLETHANES | MERCK PATENT GmbH (DE) | 1991-01-16 | — | — | EP | disclosed |