Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796501 | 0.87 | ATM (0.47) | RAB9ANPC1ATMMAPTHPGD | |
| SCHEMBL9796527 | 0.84 | RAB9A (0.50) | RAB9ANPC1ATMMAPTHPGD | |
| SCHEMBL9796538 | 0.83 | RAB9A (0.54) | RAB9ANPC1MAPTHPGDL3MBTL1 | |
| SCHEMBL9796437 | 0.82 | RAB9A (0.44) | RAB9ANPC1MAPTHPGDL3MBTL1 | |
| SCHEMBL9796412 | 0.82 | NPC1 (0.44) | RAB9ANPC1MAPTHPGDL3MBTL1 | |
| SCHEMBL9796460 | 0.74 | GSK3B (0.35) | RAB9AMAPK1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9796455 | 0.73 | RAB9A (0.49) | RAB9ANPC1MAPTHPGDL3MBTL1 | |
| SCHEMBL9796520 | 0.70 | TSHR (0.34) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL83331 | 0.68 | RAB9A (0.79) | RAB9ANPC1MAPTHPGDL3MBTL1 | |
| SCHEMBL29043248 | 0.66 | RAB9A (0.77) | RAB9ANPC1MAPTHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997840-A | Quinolone sulphonates having antihypertensive activity | THE BOOTS COMPANY, PLC (GB) | 1991-03-05 | — | — | US | disclosed |
| WO-1989007593-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1989-08-24 | — | — | WO | disclosed |