Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796538 | 0.86 | RAB9A (0.54) | RAB9ANPC1HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9796455 | 0.85 | RAB9A (0.49) | RAB9ANPC1HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9796501 | 0.85 | ATM (0.47) | RAB9ANPC1HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9796437 | 0.85 | RAB9A (0.44) | RAB9ANPC1HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9796488 | 0.84 | RAB9A (0.45) | RAB9ANPC1HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9796412 | 0.80 | NPC1 (0.44) | RAB9ANPC1HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9796524 | 0.77 | KMT2A (0.40) | L3MBTL1ALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL9796448 | 0.75 | ALDH1A1 (0.42) | RAB9ANPC1ALDH1A1KDM4EGAA | |
| SCHEMBL5524626 | 0.74 | ALDH1A1 (0.48) | HPGDALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL7557302 | 0.73 | KMT2A (0.59) | HPGDL3MBTL1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997840-A | Quinolone sulphonates having antihypertensive activity | THE BOOTS COMPANY, PLC (GB) | 1991-03-05 | — | — | US | disclosed |
| EP-0330340-A1 | Therapeutic agents | The Boots Company PLC (GB) | 1989-08-30 | — | — | EP | disclosed |
| WO-1989007593-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1989-08-24 | — | — | WO | disclosed |