Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796401 | 0.82 | ALDH1A1 (0.39) | GSK3BALDH1A1MAPK1HIF1ARAB9A | |
| SCHEMBL9722935 | 0.82 | ALDH1A1 (0.39) | GSK3BALDH1A1MAPK1HIF1ARAB9A | |
| SCHEMBL9796520 | 0.80 | TSHR (0.34) | ALDH1A1HTTSMN1; SMN2ERN1POLB | |
| SCHEMBL9796593 | 0.77 | ALDH1A1 (0.54) | GSK3BALDH1A1MAPK1HIF1ARAB9A | |
| SCHEMBL9796449 | 0.77 | RAB9A (0.46) | GSK3BALDH1A1MAPK1HIF1ARAB9A | |
| SCHEMBL9796608 | 0.76 | MAPT (0.36) | GSK3BALDH1A1RAB9AMITFHTT | |
| SCHEMBL9796448 | 0.74 | ALDH1A1 (0.42) | GSK3BALDH1A1MAPK1HIF1ARAB9A | |
| SCHEMBL9796488 | 0.74 | RAB9A (0.45) | ALDH1A1MAPK1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2795538 | 0.72 | GSK3B (0.44) | GSK3BALDH1A1MAPK1HIF1ARAB9A | |
| SCHEMBL9516561 | 0.69 | ALDH1A1 (0.55) | GSK3BALDH1A1MAPK1HIF1ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997840-A | Quinolone sulphonates having antihypertensive activity | THE BOOTS COMPANY, PLC (GB) | 1991-03-05 | — | — | US | disclosed |
| WO-1989007593-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1989-08-24 | — | — | WO | disclosed |