Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850763 | 0.84 | CLK4 (0.44) | CLK4DYRK1AADRB2CYP2A6HCRTR1 | |
| SCHEMBL13285705 | 0.83 | PTGS2 (0.41) | PTGS2MAPTLMNAGAASMN1; SMN2 | |
| SCHEMBL29383868 | 0.82 | PTGS2 (0.57) | PTGS2MAPTGAASMN1; SMN2MEN1 | |
| SCHEMBL5393111 | 0.82 | PTGS2 (0.57) | PTGS2MAPTGAASMN1; SMN2MEN1 | |
| SCHEMBL29477070 | 0.82 | PTGS2 (0.57) | PTGS2MAPTGAASMN1; SMN2MEN1 | |
| SCHEMBL9796794 | 0.81 | HRH3 (0.52) | PTGS2LMNASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL29725141 | 0.81 | HRH3 (0.52) | PTGS2LMNASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL21390635 | 0.80 | KDM4E (0.47) | PTGS2MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10590683 | 0.79 | ADRB2 (0.57) | CLK4ADRB2MAPTLMNAGAA | |
| SCHEMBL6848165 | 0.79 | CLK4 (0.47) | CLK4DYRK1AADRB2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047172-A | W-substituted, optically active alkanol ester derivatives | CHISSO CORPORATION (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0257457-B1 | OPTICALLY ACTIVE 2-METHYL 1,3-PROPANEDIOL DERIVATIVES, LIQUID CRYSTAL COMPOSITIONS COMPRISING THEM AND OPTICAL SWITCHING ELEMENT | Chisso Corporation (JP) | 1990-10-31 | — | — | EP | disclosed |
| EP-0257457-A2 | Optically active 2-methyl 1,3-propanediol derivatives, liquid crystal compositions comprising them and optical switching element | Chisso Corporation (JP) | 1988-03-02 | — | — | EP | disclosed |