Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913341 | 0.71 | CSNK2A1 (0.47) | PIM3PARP15TNKS2TNKSPARP1 | |
| SCHEMBL8159994 | 0.70 | HSD17B10 (0.49) | MAPK1PIM3HTR2AHTR2CHTR2B | |
| SCHEMBL6332699 | 0.70 | ALDH1A1 (0.42) | MAPK1PIM3HTR2AHTR2CHTR2B | |
| SCHEMBL6633037 | 0.70 | ALDH1A1 (0.42) | MAPK1PIM3HTR2AHTR2CHTR2B | |
| SCHEMBL2040397 | 0.69 | MAPK1 (1.00) | MAPK1PIM3ALDH1A1MEN1KMT2A | |
| SCHEMBL13229579 | 0.67 | ALDH1A1 (0.41) | MAPK1HTR2AHTR2CHTR2BPARP15 | |
| SCHEMBL2643076 | 0.66 | MAPK1 (0.64) | MAPK1PIM3HTR2AIDO1HDAC6 | |
| SCHEMBL3015057 | 0.66 | PIM3 (0.52) | MAPK1PIM3PARP15PARP1HTT | |
| SCHEMBL2037236 | 0.66 | PIM3 (0.59) | MAPK1PIM3RAB9A | |
| SCHEMBL14631235 | 0.66 | MAPK1 (0.64) | MAPK1PIM3ALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021543-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021543-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS PESTICIDES | DDT, TYR, CAT | MAPK1 4441/4885PIM3 2012/4885HTR2A 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.