Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344390 | 0.80 | PTGS2 (0.71) | MEN1KMT2ALMNAPTGS2CYP3A4 | |
| SCHEMBL30593451 | 0.80 | PTGS2 (0.71) | MEN1KMT2ALMNAPTGS2CYP3A4 | |
| SCHEMBL11520899 | 0.79 | LMNA (0.58) | MEN1KMT2ALMNAPTGS2CYP3A4 | |
| SCHEMBL4427765 | 0.78 | CHRM1 (0.54) | MEN1KMT2ALMNAPTGS2CYP3A4 | |
| SCHEMBL29481378 | 0.78 | CHRM1 (0.54) | MEN1KMT2ALMNAPTGS2CYP3A4 | |
| Hydrochloric Acid SCHEMBL2584597 | 0.77 | CHRM1 (0.53) | MEN1KMT2ALMNAPTGS2CYP3A4 | |
| SCHEMBL10504416 | 0.76 | LMNA (0.54) | MEN1KMT2ALMNAPTGS2CYP3A4 | |
| Acetic Acid SCHEMBL28343505 | 0.75 | LMNA (0.54) | MEN1KMT2ALMNAPTGS2CYP3A4 | |
| SCHEMBL11521221 | 0.75 | LMNA (0.53) | MEN1KMT2ALMNAPTGS2CYP3A4 | |
| SCHEMBL10503599 | 0.75 | LMNA (0.53) | MEN1KMT2ALMNAPTGS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073641-A | PRODRUG DERIVATIVES OF CARBOXYLIC ACID DRUGS | BUNDGAARD HANS (DK) | 1991-12-17 | — | — | US | disclosed |
| EP-0278977-A1 | PRODRUG DERIVATIVES OF CARBOXYLIC ACID DRUGS. | BUNDGAARD HANS (DK) | 1988-08-24 | — | — | EP | disclosed |
| WO-1988001615-A1 | PRODRUG DERIVATIVES OF CARBOXYLIC ACID DRUGS | BUNDGAARD HANS (DK) | 1988-03-10 | — | — | WO | disclosed |