Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29481378 | 1.00 | CHRM1 (0.54) | CHRM1LMNAPTGS2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2584597 | 0.99 | CHRM1 (0.53) | CHRM1LMNAPTGS2MEN1KMT2A | |
| Acetic Acid SCHEMBL28343505 | 0.97 | LMNA (0.54) | CHRM1LMNAPTGS2MEN1KMT2A | |
| Mefenamic Acid SCHEMBL28343523 | 0.86 | LMNA (0.63) | CHRM1LMNAPTGS2MEN1KMT2A | |
| SCHEMBL9576565 | 0.81 | SCN1A (0.63) | CHRM1LMNAMEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL29471312 | 0.80 | SCN1A (0.61) | CHRM1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL3805715 | 0.80 | MT-CO2 (0.59) | CHRM1LMNAPTGS2MEN1KMT2A | |
| SCHEMBL29481381 | 0.79 | METTL3 (0.76) | CHRM1LMNAPTGS2MEN1KMT2A | |
| SCHEMBL4434232 | 0.79 | METTL3 (0.76) | CHRM1LMNAPTGS2MEN1KMT2A | |
| SCHEMBL9797153 | 0.78 | MEN1 (0.57) | CHRM1LMNAPTGS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104706630-B | Positively charged water-soluble prodrugs of aryl anthranilic acids with fast skin penetration rates | 于崇曦 | 2020-01-10 | — | — | CN | disclosed |
| EP-2084132-A1 | POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF N-ARYLANTHRANILIC ACIDS WITH VERY FAST SKIN PENETRATION RATE | Techfields Biochem Co. Ltd (CN) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008029199-A1 | POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF N-ARYLANTHRANILIC ACIDS WITH VERY FAST SKIN PENETRATION RATE | TECHFIELDS BIOCHEM CO. LTD (CN) | 2008-03-13 | — | — | WO | disclosed |