Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752732 | 0.81 | GABRA1 (0.64) | PLAUGABRA1GABRA5GABRB2SMN1; SMN2 | |
| SCHEMBL9797571 | 0.79 | GABRA1 (0.59) | PLAUGABRA1GABRA5GABRB2SMN1; SMN2 | |
| SCHEMBL20579952 | 0.77 | GABRA1 (0.66) | GABRA1GABRA5GABRB2SMN1; SMN2RAB9A | |
| SCHEMBL9788648 | 0.73 | RAB9A (0.55) | GABRA1GABRB2SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL10465838 | 0.73 | GABRA1 (0.50) | GABRA1GABRB2RAB9AKDM4ENPC1 | |
| SCHEMBL31073619 | 0.72 | PLAU (0.46) | PLAUSMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10466564 | 0.71 | GABRA1 (0.51) | GABRA1GABRB2KDM4EALDH1A1 | |
| SCHEMBL24670283 | 0.71 | HPGD (0.73) | SMN1; SMN2CYP1A2CYP2C19RAB9AKDM4E | |
| SCHEMBL9788618 | 0.71 | GABRA1 (0.47) | GABRA1GABRB2SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL9788650 | 0.71 | GABRA1 (0.45) | GABRA1GABRB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064836-A | Imidazopyridine for use as an anaesthetic | SYNTHELABO (FR) | 1991-11-12 | — | — | US | disclosed |