Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081392 | 0.86 | HRH3 (0.39) | SIGMAR1SMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL87801 | 0.86 | — | — | |
| SCHEMBL486492 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL28067318 | 0.84 | SIGMAR1 (0.39) | SIGMAR1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Bromide SCHEMBL10332289 | 0.84 | HRH3 (0.38) | SIGMAR1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Iodide SCHEMBL28911088 | 0.84 | SMN1; SMN2 (0.38) | SIGMAR1SMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| Bromide SCHEMBL1471663 | 0.84 | HRH3 (0.38) | SIGMAR1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Ammonia Solution, Strong SCHEMBL1934293 | 0.84 | HRH3 (0.38) | SIGMAR1SMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL88222 | 0.83 | — | — | |
| SCHEMBL1489209 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0208455-B1 | PROCESS FOR THE PRODUCTION OF 2,2,6,6-TETRAALKYL-4-PIPERIDYLAMINES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1991-01-30 | — | — | EP | disclosed |
| EP-0208455-A1 | Process for the production of 2,2,6,6-tetraalkyl-4-piperidylamines | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1987-01-14 | — | — | EP | disclosed |