Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 14/20 | 0.80 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.80 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.73 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989441 | 0.92 | OPRM1 (0.82) | OPRM1CACNA1COPRD1OPRK1OPRL1 | |
| Remifentanil SCHEMBL17874058 | 0.89 | CACNA1C (1.00) | OPRM1CACNA1COPRD1OPRK1 | |
| Remifentanil SCHEMBL36652 | 0.89 | CACNA1C (1.00) | OPRM1CACNA1COPRD1OPRK1 | |
| Remifentanil SCHEMBL3711219 | 0.88 | CACNA1C (0.98) | OPRM1CACNA1COPRD1OPRK1 | |
| Remifentanil SCHEMBL41242 | 0.88 | CACNA1C (0.98) | OPRM1CACNA1COPRD1OPRK1 | |
| Remifentanil SCHEMBL29846323 | 0.88 | CACNA1C (0.98) | OPRM1CACNA1COPRD1OPRK1 | |
| Remifentanil SCHEMBL3423820 | 0.88 | CACNA1C (0.98) | OPRM1CACNA1COPRD1OPRK1 | |
| SCHEMBL11563541 | 0.87 | OPRM1 (0.82) | OPRM1CACNA1COPRD1OPRK1 | |
| Remifentanil SCHEMBL1649640 | 0.87 | CACNA1C (0.96) | OPRM1CACNA1COPRD1OPRK1 | |
| Remifentanil SCHEMBL27828413 | 0.87 | CACNA1C (0.96) | OPRM1CACNA1COPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019583-A | N-phenyl-N-(4-piperidinyl)amides useful as analgesics | GLAXO INC. (US) | 1991-05-28 | — | — | US | disclosed |