Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798050 | 1.00 | KDM1A (0.52) | KDM1AEGLN2CYP11B1KDM4EALDH1A1 | |
| SCHEMBL9798188 | 0.89 | DGAT1 (0.42) | KDM1ADGAT1 | |
| SCHEMBL9798177 | 0.89 | DGAT1 (0.42) | KDM1ADGAT1 | |
| SCHEMBL9676427 | 0.86 | EGLN2 (0.40) | KDM1AEGLN2HRH2HRH1HRH3 | |
| SCHEMBL10890212 | 0.86 | EGLN2 (0.40) | KDM1AEGLN2HRH2HRH1HRH3 | |
| SCHEMBL9805337 | 0.86 | KDM1A (0.48) | KDM1AEGLN2CYP11B1KDM4EALDH1A1 | |
| SCHEMBL9805343 | 0.86 | KDM1A (0.48) | KDM1AEGLN2CYP11B1KDM4EALDH1A1 | |
| SCHEMBL20924205 | 0.86 | KDM1A (0.67) | KDM1AEGLN2CYP11B1KDM4EALDH1A1 | |
| SCHEMBL9798346 | 0.85 | HRH3 (0.41) | EGLN2HRH2HRH1HRH3 | |
| SCHEMBL9798359 | 0.85 | HRH3 (0.41) | EGLN2HRH2HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240320-B1 | PHENYLPYRIDINE DERIVATIVES | Chisso Corporation (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4772416-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1988-09-20 | — | — | US | disclosed |