Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405551 | 0.80 | MAPT (0.70) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL1405552 | 0.80 | MAPT (0.70) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9798875 | 0.79 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9798869 | 0.79 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9798724 | 0.79 | ALDH3A1 (0.65) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8297702 | 0.78 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL16577117 | 0.78 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9798768 | 0.76 | ALDH3A1 (0.55) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8849524 | 0.76 | ALDH1A1 (0.48) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8849529 | 0.76 | ALDH1A1 (0.48) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411103-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK PATENT GmbH (DE) | 1991-02-06 | — | — | EP | disclosed |
| WO-1990009616-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |