Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849524 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL10335465 | 0.82 | MAPT (0.45) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL10336239 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNATDP1POLB | |
| SCHEMBL9632491 | 0.77 | DTYMK (0.49) | MAPTNPC1RAB9APOLBBACE1 | |
| SCHEMBL7288138 | 0.76 | ALDH5A1 (0.57) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL5594752 | 0.76 | PLA2G4A (0.50) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL5594757 | 0.76 | PLA2G4A (0.50) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL5594749 | 0.76 | PLA2G4A (0.50) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9798323 | 0.76 | MAPT (0.53) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| Dimethylamine SCHEMBL8849700 | 0.75 | TRPV1 (0.46) | ALDH1A1MAPTMAPK1L3MBTL1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583417-B1 | CROSSLINKED POLED POLYMERS FOR NONLINEAR OPTIC APPLICATIONS AND METHOD OF MAKING THEM | DU PONT (US) | 1997-01-29 | — | — | EP | claimed |