SCHEMBL979851

SCHEMBL979851

Nc1ccc(CCCO)cc1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GFER P55789 1/20 0.62
▸ MAOB P27338 4/20 0.60
▸ CA2 P00918 4/20 0.55
▸ MAOA P21397 2/20 0.52
▸ ALDH1A1 P00352 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ TSHR P16473 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ CYP4A11 Q02928 1/20 0.47
▸ LOXL2 Q9Y4K0 1/20 0.46
▸ LTA4H P09960 1/20 0.46
▸ EPHX2 P34913 1/20 0.46
▸ CYP19A1 P11511 1/20 0.45
▸ RECQL P46063 1/20 0.43
▸ SIGMAR1 Q99720 1/20 0.43
▸ HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7140170 0.93 GFER (0.54) GFERMAOBCA2MAOAALDH1A1
SCHEMBL4281793 0.93 MAOB (0.64) GFERMAOBCA2MAOAALDH1A1
SCHEMBL4300050 0.91 MAOB (0.61) GFERMAOBCA2MAOAALDH1A1
SCHEMBL2380716 0.91 MAOB (0.61) GFERMAOBCA2MAOAALDH1A1
SCHEMBL9806863 0.91 MAOB (0.61) GFERMAOBCA2MAOAALDH1A1
SCHEMBL1452380 0.91 MAOB (0.61) GFERMAOBCA2MAOAALDH1A1
SCHEMBL10357817 0.91 MAOB (0.61) GFERMAOBCA2MAOAALDH1A1
SCHEMBL239040 0.87 CA2 (0.60) CA2ALDH1A1CYP3A4TDP1CYP4A11
SCHEMBL1049854 0.85 HTR2A (0.60) CA2ALDH1A1TDP1CYP4A11LOXL2
SCHEMBL6051 0.84 GFER (0.68) GFERMAOBCA2MAOAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117451808-A Titanium nitride microelectrode array, preparation method and multichannel molecular detection device 上海新微技术研发中心有限公司 2024-01-26 — — CN claimed
EP-1799791-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-01-13 — — EP claimed
US-4904275-A OXIDIZER L'OREAL (FR) 1990-02-27 — — US claimed
US-12264169-B2 Heteroaryl inhibitors of PDE4 Tetra Discovery Partners (US) 2025-04-01 — — US disclosed
WO-2025054339-A1 TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT ARCUS BIOSCIENCES, INC. (US) 2025-03-13 — — WO disclosed
CN-118871548-A Photoalignment materials 罗利克技术有限公司 2024-10-29 — — CN disclosed
US-20240287076-A1 COMPOUNDS FOR TARGETING DEGRADATION OF BRUTON'S TYROSINE KINASE C4 THERAPEUTICS, INC. 2024-08-29 — — US disclosed
CN-118530557-A High-heat-conductivity plastic for energy-saving LED light source and preparation method thereof 江苏德海汽车科技股份有限公司 2024-08-23 — — CN disclosed
WO-2024117789-A1 PLK1 DEGRADATION INDUCING COMPOUNDS WITH INCREASED RIGIDITY UPPTHERA, INC. (KR) 2024-06-06 — — WO disclosed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 — — CN disclosed
EP-4333899-A1 COMPOUNDS FOR TARGETING DEGRADATION OF BRUTON'S TYROSINE KINASE Biogen MA Inc. (US) 2024-03-13 — — EP disclosed
EP-0564924-A2 2-Oxoethyl derivatives as immunosuppressants Bayer Corporation (US) 1993-10-13 — — EP disclosed
EP-0511879-A1 Pyrazine derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-04 — — EP disclosed
EP-0257616-B1 DIHYDROPYRIDINE DERIVATES AND PHARMACEUTICAL COMPOSITION THEREOF THE GREEN CROSS CORPORATION (JP) 1992-10-28 — — EP disclosed
US-4987132-A PLATELET ACTIVATING FACTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1991-01-22 — — US disclosed
US-4886819-A TREATMENT OF HYPERTENSION AND PROPHYLAXIS THE GREEN CROSS CORPORATION (JP) 1989-12-12 — — US disclosed
CN-1030415-A Saturated heterocycle carboxamide derivatives and its preparation method YAMANOUCHI PHARMA CO LTD (JP) 1989-01-18 — — CN disclosed
EP-0279681-A2 Saturated heterocyclic carboxamide derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-08-24 — — EP disclosed
EP-0257616-A2 Dihydropyridine derivates and pharmaceutical composition thereof THE GREEN CROSS CORPORATION (JP) 1988-03-02 — — EP disclosed
US-4332809-A ANTIALLERGENS TANABE SEIYAKU CO., LTD. (JP) 1982-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12264169-B2 Heteroaryl inhibitors of PDE4 PDE4A, PDE4B, PDE4C GFER 2160/4885MAOB 629/4885CA2 2235/4885
US-20240287076-A1 COMPOUNDS FOR TARGETING DEGRADATION OF BRUTON'S TYROSINE KINASE BTK, SYK, LYN GFER 3335/4885MAOB 1537/4885CA2 4773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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