Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300050 | 1.00 | MAOB (0.61) | MAOBCA2GFERMAOACYP4F2 | |
| SCHEMBL10357817 | 1.00 | MAOB (0.61) | MAOBCA2GFERMAOACYP4F2 | |
| SCHEMBL2380716 | 1.00 | MAOB (0.61) | MAOBCA2GFERMAOACYP4F2 | |
| SCHEMBL1452380 | 1.00 | MAOB (0.61) | MAOBCA2GFERMAOACYP4F2 | |
| SCHEMBL4281793 | 0.98 | MAOB (0.64) | MAOBCA2GFERMAOACYP4F2 | |
| SCHEMBL979851 | 0.91 | GFER (0.62) | MAOBCA2GFERMAOACYP4A11 | |
| SCHEMBL23837668 | 0.88 | CA2 (0.63) | CA2CYP4F2CYP4A11HTR2AALDH1A1 | |
| SCHEMBL4021564 | 0.88 | MAOB (0.76) | MAOBGFERMAOAHTR2AALDH1A1 | |
| SCHEMBL20251158 | 0.88 | MAOB (0.76) | MAOBGFERMAOAHTR2AALDH1A1 | |
| SCHEMBL4020067 | 0.88 | MAOB (0.76) | MAOBGFERMAOAHTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061780-A | Poly(ether-bis-imide-spiro dilactam) polymer | SHELL OIL COMPANY (US) | 1991-10-29 | — | — | US | disclosed |
| US-5053518-A | Hydroxy-substituted cyclic-1,6-diaza[4.4]spirodilactams | SHELL OIL COMPANY (US) | 1991-10-01 | — | — | US | disclosed |
| US-4939251-A | Novel spirolactones | SHELL OIL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |