SCHEMBL4281793

SCHEMBL4281793

Nc1ccc(CCCCO)cc1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.64
GFER P55789 1/20 0.59
CA2 P00918 3/20 0.57
MAOA P21397 2/20 0.50
CYP4F2 P78329 1/20 0.48
CYP4A11 Q02928 1/20 0.48
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.44
HTR2A P28223 1/20 0.43
CYP19A1 P11511 1/20 0.43
RECQL P46063 1/20 0.42
LTB4R Q15722 1/20 0.42
SIGMAR1 Q99720 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9806863 0.98 MAOB (0.61) MAOBGFERCA2MAOACYP4F2
SCHEMBL1452380 0.98 MAOB (0.61) MAOBGFERCA2MAOACYP4F2
SCHEMBL2380716 0.98 MAOB (0.61) MAOBGFERCA2MAOACYP4F2
SCHEMBL10357817 0.98 MAOB (0.61) MAOBGFERCA2MAOACYP4F2
SCHEMBL4300050 0.98 MAOB (0.61) MAOBGFERCA2MAOACYP4F2
SCHEMBL979851 0.93 GFER (0.62) MAOBGFERCA2MAOACYP4A11
SCHEMBL3111509 0.87 MAOB (0.80) MAOBGFERMAOAALDH1A1CYP3A4
SCHEMBL242504 0.87 CA2 (0.61) MAOBCA2CYP4F2CYP4A11ALDH1A1
SCHEMBL7140170 0.86 GFER (0.54) MAOBGFERCA2MAOACYP4A11
SCHEMBL10451946 0.86 HTR2A (0.59) CA2MAOACYP4F2CYP4A11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920343-B2 Method for producing aniline derivative by fermentation from carbon source JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2018-03-20 US claimed
US-20170022528-A1 METHOD FOR PRODUCING ANILINE DERIVATIVE BY FERMENTATION FROM CARBON SOURCE JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2017-01-26 US claimed
EP-3121275-A1 METHOD FOR PRODUCING ANILINE DERIVATIVE BY FERMENTATION FROM CARBON SOURCE Japan Science and Technology Agency (JP) 2017-01-25 EP claimed
US-12286426-B2 Heterocyclic mitochondrial activity inhibitors and uses thereof Université de Montréal (CA) 2025-04-29 US disclosed
EP-3704111-B1 HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF UNIV MONTREAL (CA) 2024-10-09 EP disclosed
US-12065421-B2 Inhibitors of oplophorus luciferase-derived bioluminescent complexes PROMEGA CORPORATION (US) 2024-08-20 US disclosed
EP-4140991-B1 INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES PROMEGA CORP (US) 2024-05-15 EP disclosed
CN-111886234-B Heterocyclic mitochondrial activity inhibitors and uses thereof 蒙特利尔大学 2023-12-15 CN disclosed
US-20230357221-A1 HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF UNIV MONTREAL (CA) 2023-11-09 US disclosed
US-20230357221-A1 HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF UNIV MONTREAL (CA) 2023-11-09 US disclosed
US-20230357221-A1 HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF UNIV MONTREAL (CA) 2023-11-09 US disclosed
EP-0131302-B1 IMIDAZOLIUM SALTS, INTERMEDIATES THERETO AND THEIR USE SCHERING AKTIENGESELLSCHAFT (DE) 1992-01-29 EP disclosed
US-4853382-A TREATING ASTHMA AND BRONCHITIS GLAXO GROUP LIMITED (GB) 1989-08-01 US disclosed
EP-0178919-B1 AMINOPHENOL DERIVATIVES GLAXO GROUP LIMITED (GB) 1988-12-21 EP disclosed
US-4730008-A STIMULANT FOR BETA-ADRENORECEPTORS GLAXO GROUP LIMITED (GB) 1988-03-08 US disclosed
CN-86102681-A The preparation method of p-aminophenol derivative and purposes 1987-10-28 CN disclosed
US-4689341-A Antiarrhythmic imidazoles SCHERING A.G. (DE) 1987-08-25 US disclosed
US-4613609-A Antiarrhythmic imidazoliums SCHERING A. G. (DE) 1986-09-23 US disclosed
US-4581370-A Antiarrhythmic imidazoliums SCHERING A.G. (DE) 1986-04-08 US disclosed
EP-0131302-A2 Imidazolium salts, intermediates thereto and their use SCHERING AKTIENGESELLSCHAFT (DE) 1985-01-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357221-A1 HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF IDH2, TFAM, IDH1 MAOB 3874/4885GFER 4248/4885CA2 425/4885
US-12065421-B2 Inhibitors of oplophorus luciferase-derived bioluminescent complexes LUC7L2, LYPLAL1, GUSB MAOB 2567/4885GFER 3510/4885CA2 3483/4885
US-12286426-B2 Heterocyclic mitochondrial activity inhibitors and uses thereof IDH2, TFAM, IDH1 MAOB 3874/4885GFER 4248/4885CA2 425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.