Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798975 | 0.86 | MAPT (0.46) | ALDH1A1RECQLHSD17B10APPMAPT | |
| SCHEMBL9798425 | 0.85 | MAPT (0.51) | ALDH1A1MAPTMAPK1POLBKDM4E | |
| SCHEMBL9798455 | 0.85 | MAPT (0.51) | ALDH1A1MAPTMAPK1POLBKDM4E | |
| SCHEMBL9798449 | 0.85 | MAPT (0.51) | ALDH1A1MAPTMAPK1POLBKDM4E | |
| SCHEMBL9798431 | 0.85 | MAPT (0.51) | ALDH1A1MAPTMAPK1POLBKDM4E | |
| SCHEMBL9798913 | 0.84 | ALDH1A1 (0.50) | ALDH1A1RECQLHSD17B10APPMAPT | |
| SCHEMBL9587808 | 0.84 | VCAM1 (0.46) | ALDH1A1RECQLHSD17B10MAPTTDP1 | |
| SCHEMBL9798937 | 0.84 | MAPT (0.38) | ALDH1A1RECQLHSD17B10APPMAPT | |
| SCHEMBL9798747 | 0.82 | MAPT (0.42) | ALDH1A1APPMAPTTDP1MAPK1 | |
| SCHEMBL9798492 | 0.82 | TDP1 (0.44) | ALDH1A1RECQLHSD17B10MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411103-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK PATENT GmbH (DE) | 1991-02-06 | — | — | EP | disclosed |
| WO-1990009616-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |