Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.55 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.55 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10496471 | 1.00 | TRPA1 (0.56) | TRPA1TRPM8GRIK1GRIA1GRIA2 | |
| SCHEMBL1019981 | 0.87 | GRIK1 (0.58) | TRPA1GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL29542528 | 0.87 | GRIK1 (0.58) | TRPA1GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL2291774 | 0.87 | GRIK1 (0.58) | TRPA1GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL13554389 | 0.87 | GRIK1 (0.58) | TRPA1GRIK1GRIA1GRIA2GRIA3 | |
| Hydrochloric Acid SCHEMBL26105180 | 0.85 | GRIK1 (0.56) | TRPA1GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL68551 | 0.84 | GRIK1 (0.56) | TRPA1GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL68552 | 0.84 | GRIK1 (0.56) | TRPA1GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL70201 | 0.83 | ALDH1A1 (0.62) | TRPA1TRPM8GRIK1GRIA1GRIA2 | |
| SCHEMBL8902281 | 0.83 | ALDH1A1 (0.62) | TRPA1TRPM8GRIK1GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275501-B1 | PROCESS FOR THE PREPARATION OF (Z)-2-(2-ARYLETHENYL)-ARYLCARBOXYLIC ACIDS | BASF Aktiengesellschaft (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4857658-A | Preparation of (Z)-2-(2-arylethenyl)arylcarboxylic acids | BASF AKTIENGESELLSCHAFT (DE) | 1989-08-15 | — | — | US | disclosed |
| EP-0275501-A1 | Process for the preparation of (Z)-2-(2-arylethenyl)-arylcarboxylic acids | BASF Aktiengesellschaft (DE) | 1988-07-27 | — | — | EP | disclosed |