Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14242912 | 0.90 | FDPS (0.51) | FDPSL3MBTL1DRD2ALDH1A1ABL1 | |
| SCHEMBL7442904 | 0.88 | FDPS (0.50) | FDPSL3MBTL1DRD2ALDH1A1ABL1 | |
| SCHEMBL14336130 | 0.88 | HSD17B10 (0.55) | FDPSL3MBTL1DRD2ALDH1A1ABL1 | |
| SCHEMBL9306342 | 0.87 | S1PR2 (0.53) | FDPS | |
| SCHEMBL4189413 | 0.87 | FDPS (0.54) | FDPSL3MBTL1DRD2ALDH1A1ABL1 | |
| SCHEMBL3782064 | 0.86 | LMNA (0.55) | FDPSDRD2ALDH1A1ABL1RIN1 | |
| SCHEMBL908271 | 0.85 | ABL1 (0.59) | L3MBTL1DRD2ALDH1A1ABL1RIN1 | |
| SCHEMBL14331177 | 0.82 | KDM4E (0.55) | FDPSALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL4842427 | 0.81 | PTGER3 (0.52) | ALDH1A1GAAMAPTCYP1A2CYP3A4 | |
| SCHEMBL14262533 | 0.80 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1ABL1RIN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061720-A | ANTIINFLAMMATORY AGENTS FOR TOPICAL APPLICATION TO SKIN | A. H. ROBINS COMPANY, INC. (US) | 1991-10-29 | — | — | US | disclosed |