Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 10/20 | 0.59 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.59 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.59 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27718639 | 0.86 | MAPK13 (0.59) | MAPK14MAPK13MAPK12MAPK11TAS2R14 | |
| SCHEMBL9798813 | 0.86 | FABP4 (0.60) | MAPK14MAPK13MAPK12MAPK11TAS2R14 | |
| SCHEMBL27509293 | 0.82 | MAPK14 (0.75) | MAPK14MAPK13MAPK12MAPK11TAS2R14 | |
| SCHEMBL7097760 | 0.78 | MAPK13 (0.61) | MAPK14MAPK13MAPK12MAPK11TAS2R14 | |
| SCHEMBL27718637 | 0.77 | MAPK13 (0.59) | MAPK14MAPK13MAPK12MAPK11TAS2R14 | |
| SCHEMBL22563033 | 0.77 | MAPK14 (0.47) | MAPK14MAPK13MAPK12MAPK11TDP1 | |
| SCHEMBL31426816 | 0.76 | TDP1 (0.56) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL4186922 | 0.76 | AKR1C3 (0.60) | TAS2R14FABP4MEN1AKR1C3AKR1C2 | |
| SCHEMBL11581567 | 0.76 | MEN1 (0.59) | FABP4MEN1AKR1C3AKR1C2KMT2A | |
| SCHEMBL13973364 | 0.76 | TDP1 (0.56) | MAPK14MAPK13MAPK12MAPK11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008379-A | Water soluble anionic dyes; lightfast brown color on leather | SANDOZ LTD. (CH) | 1991-04-16 | — | — | US | disclosed |