Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 13/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 13/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 13/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563067 | 0.86 | RAPGEF4 (0.38) | MAPK14MAPK13MAPK12MAPK11TDP1 | |
| SCHEMBL9799041 | 0.77 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL22562963 | 0.72 | MAPK14 (0.39) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL31426816 | 0.71 | TDP1 (0.56) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL13973364 | 0.71 | TDP1 (0.56) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL27718637 | 0.69 | MAPK13 (0.59) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7567075 | 0.67 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL27718639 | 0.66 | MAPK13 (0.59) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL108882 | 0.66 | MAPT (0.54) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL29653984 | 0.66 | MAPT (0.54) | MAPK14MAPK13MAPK12MAPK11GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725777-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2020-10-21 | — | — | EP | disclosed |