Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.32 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074817 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL31500547 | 0.77 | LMNA (0.40) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL16555940 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL6299575 | 0.75 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL10430860 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL9798590 | 0.73 | SMN1; SMN2 (0.47) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL10941731 | 0.73 | ALDH1A1 (0.42) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL3628365 | 0.73 | ALDH1A1 (0.52) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL4457225 | 0.73 | TSHR (0.45) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL30599573 | 0.73 | ALDH1A1 (0.52) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010094-A | Imidazolyl compounds and their use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| EP-0379871-A2 | Azolyl derivatives | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |