Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15309635 | 0.81 | SRC (0.55) | — | |
| SCHEMBL4299513 | 0.79 | KDM4E (0.43) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| Bromide SCHEMBL2699120 | 0.78 | KDM4E (0.42) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29878298 | 0.78 | PKM (0.54) | TDP1KDM4EALDH1A1HPGDPTGDR2 | |
| SCHEMBL28659540 | 0.78 | PKM (0.54) | TDP1KDM4EALDH1A1HPGDPTGDR2 | |
| SCHEMBL3984932 | 0.77 | TDP1 (0.46) | TDP1TSHRKDM4EHIF1ACYP2C19 | |
| SCHEMBL9379478 | 0.77 | KDM4E (0.46) | TDP1TSHRKDM4ECYP2C19MAPT | |
| SCHEMBL2112736 | 0.76 | KDM4E (0.58) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| Benzene SCHEMBL1532355 | 0.76 | KDM4E (0.46) | TDP1KDM4EALDH1A1HPGDPPARG | |
| SCHEMBL29878429 | 0.75 | MET (0.54) | KDM4ENPSR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026700-A | Certain quinolines and thienopyridines as excitatory amino acid antagonists | MERRELL DOW PHARMACEUTICALS (US) | 1991-06-25 | — | — | US | disclosed |