Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983777 | 0.80 | TDP1 (0.55) | TDP1TSHRMAPTPTGDR2PTGDR | |
| SCHEMBL9799138 | 0.77 | TDP1 (0.50) | TDP1TSHRMAPTPTGDR2KDM4E | |
| SCHEMBL3989100 | 0.77 | THRB (0.46) | TDP1TSHRKDM4CMAPTPTGDR2 | |
| SCHEMBL28659540 | 0.76 | PKM (0.54) | TDP1PTGDR2KDM4EALDH1A1HPGD | |
| SCHEMBL29878298 | 0.76 | PKM (0.54) | TDP1PTGDR2KDM4EALDH1A1HPGD | |
| SCHEMBL28670159 | 0.74 | LMNA (0.62) | PTGDR2KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL29878581 | 0.74 | LMNA (0.62) | PTGDR2KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL3778473 | 0.73 | PTGDR2 (0.45) | TDP1TSHRMAPTPTGDR2KDM4E | |
| SCHEMBL3986256 | 0.72 | TDP1 (0.43) | TDP1TSHRMAPTPTGDR2KDM4E | |
| SCHEMBL2112736 | 0.72 | KDM4E (0.58) | TDP1PTGDR2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |