Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.47 |
| ▸ | MAT2A | P31153 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | HBB | P68871 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799278 | 1.00 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2LMNAAPP | |
| SCHEMBL9798869 | 0.87 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2LMNAAPP | |
| SCHEMBL9798875 | 0.87 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2LMNAAPP | |
| SCHEMBL9798457 | 0.86 | ALDH1A1 (0.53) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9798452 | 0.86 | ALDH1A1 (0.53) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL23926475 | 0.86 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2LMNAAPP | |
| SCHEMBL9798399 | 0.84 | ALDH3A1 (0.46) | MAPTALDH1A1SMN1; SMN2LMNAAPP | |
| SCHEMBL9798392 | 0.84 | ALDH3A1 (0.46) | MAPTALDH1A1SMN1; SMN2LMNAAPP | |
| SCHEMBL9798671 | 0.82 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2LMNAAPP | |
| SCHEMBL9798677 | 0.82 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2LMNAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411103-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK PATENT GmbH (DE) | 1991-02-06 | — | — | EP | disclosed |
| WO-1990009616-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |