SCHEMBL9799290

SCHEMBL9799290

CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)c1ccc(/C=C/c2ccc(C=O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
ALDH3A1 P30838 1/20 0.58
ALDH1A3 P47895 1/20 0.58
INSR P06213 2/20 0.48
CHRM2 P08172 1/20 0.48
CHRM4 P08173 1/20 0.48
CHRM5 P08912 1/20 0.48
CHRM1 P11229 1/20 0.48
CHRM3 P20309 1/20 0.48
KDM4A O75164 4/20 0.47
KDM2A Q9Y2K7 4/20 0.47
KCNH2 Q12809 1/20 0.44
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP2A6 P11509 1/20 0.43
CYP2A13 Q16696 1/20 0.43
ATG4B Q9Y4P1 1/20 0.42
CNR2 P34972 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9799296 1.00 ALDH1A1 (0.58) ALDH1A1ALDH3A1ALDH1A3INSRCHRM2
SCHEMBL10438443 0.95 ALDH1A3 (0.63) ALDH1A1ALDH3A1ALDH1A3INSRCHRM2
SCHEMBL9875023 0.95 ALDH1A3 (0.63) ALDH1A1ALDH3A1ALDH1A3INSRCHRM2
SCHEMBL9448811 0.95 ALDH1A3 (0.63) ALDH1A1ALDH3A1ALDH1A3INSRCHRM2
SCHEMBL609500 0.95 ALDH1A3 (0.63) ALDH1A1ALDH3A1ALDH1A3INSRCHRM2
SCHEMBL1166127 0.95 ALDH1A3 (0.63) ALDH1A1ALDH3A1ALDH1A3INSRCHRM2
SCHEMBL10010380 0.93 ALDH1A1 (0.61) ALDH1A1ALDH3A1ALDH1A3INSRCHRM2
SCHEMBL10010383 0.93 ALDH1A1 (0.61) ALDH1A1ALDH3A1ALDH1A3INSRCHRM2
SCHEMBL9442184 0.93 ALDH3A1 (0.61) ALDH1A1ALDH3A1ALDH1A3INSRCHRM2
SCHEMBL4003205 0.93 ALDH1A1 (0.66) ALDH1A1ALDH3A1ALDH1A3INSRCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0411103-A1 NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS MERCK PATENT GmbH (DE) 1991-02-06 EP disclosed
WO-1990009616-A1 NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed