Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2376358 | 0.94 | TAAR1 (0.55) | TAAR1SIGMAR1KCNH2CYP1A2CHRM2 | |
| Hydrochloric Acid SCHEMBL9471912 | 0.92 | TAAR1 (0.53) | TAAR1KCNH2CYP1A2CHRM2CHRM5 | |
| SCHEMBL2376616 | 0.86 | TAAR1 (0.54) | TAAR1KCNH2CYP1A2CHRM2CHRM5 | |
| Hydrochloric Acid SCHEMBL4599895 | 0.84 | KDM4E (0.53) | TAAR1KCNH2CYP1A2CHRM2CHRM5 | |
| SCHEMBL20146704 | 0.83 | TAAR1 (0.73) | TAAR1ADRA2AADRA2BTSHRPTGS1 | |
| SCHEMBL9624239 | 0.81 | TAAR1 (0.46) | TAAR1SIGMAR1KCNH2CYP1A2CHRM2 | |
| SCHEMBL8571535 | 0.81 | TAAR1 (0.70) | TAAR1ADRA2AADRA2BTSHRPTGS1 | |
| SCHEMBL7116263 | 0.81 | TAAR1 (0.70) | TAAR1ADRA2AADRA2BTSHRPTGS1 | |
| SCHEMBL6734915 | 0.81 | TAAR1 (0.70) | TAAR1ADRA2AADRA2BTSHRPTGS1 | |
| SCHEMBL2457946 | 0.80 | DRD2 (0.52) | TAAR1KCNH2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298703-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |