Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28581591 | 0.87 | NQO1 (0.45) | FFAR4FFAR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL10625678 | 0.81 | ABL1 (0.41) | KDM4ENPC1RAB9AMAPTTP53 | |
| SCHEMBL27707567 | 0.78 | TAAR1 (0.35) | LMNATDP1TP53KMT2A | |
| SCHEMBL9686154 | 0.77 | NQO1 (0.45) | ALDH1A1KDM4ENPC1LMNARAB9A | |
| SCHEMBL17536770 | 0.77 | NQO1 (0.41) | FFAR4FFAR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL21901393 | 0.76 | KDM4E (0.66) | FFAR4FFAR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL20703325 | 0.75 | LTA4H (0.39) | FFAR4FFAR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL158260 | 0.75 | NQO1 (0.61) | ALDH1A1KDM4ENPC1RAB9ANQO1 | |
| SCHEMBL28981683 | 0.75 | NQO1 (0.61) | ALDH1A1KDM4ENPC1RAB9ANQO1 | |
| SCHEMBL27707573 | 0.75 | PTGS2 (0.35) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990621-A | Insecticides, miticides and nematocides; 3-(3-fluoro-4-phenoxyphenyl, 3-(5-fluoro-3-phenoxypyrid-2-yl) or 3-(3-methyl-4-phenyl prop-1-ene | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| US-4864027-A | INSECTICIDES, NEMATOCIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |